Effect of Pelargonium sidoides extract on upper respiratory tract diseases and on the immune response
DOI:
https://doi.org/10.35954/SM2015.34.2.5Keywords:
Bronchitis; Infections of the respiratory system; Immunomodulation; PelargoniumAbstract
Pelargonium sidoides is a popular plant originally used in Africa, within traditional medicine, in the treatment of gastrointestinal and respiratory diseases. It is currently widely used in modern medicine in upper respiratory tract infections, which are one of the most frequent syndromes at the community level, so most of the studies of the effect of the extract of this medicinal plant are focused on this aspect. The objective of this work is to provide a synthesis of the proven effects of Pelargoniun sidoides (PS) extract, mainly in the treatment of upper respiratory tract diseases, in children and adults, as well as in the prevention of possible asthma episodes after upper respiratory tract viral infections and other applications in immunology; evaluating the recommended doses and possible side effects.
In addition, we are looking to broaden the spectrum of research towards other aspects of the immune system, as well as towards another range of microorganisms, searching for new applications in the use of this extract. The current data provide evidence of effectiveness and safety in the use of PS extract in acute bronchitis and other respiratory conditions in children and adults. On the other hand, it also confirms the improvement of the immune response at various levels, with the use of this extract, as well as different mechanisms in the inhibition of bacteria and viruses. With which it is inferred the possible use of this medicinal plant in the prevention, in addition to the treatment, in case of respiratory diseases as well as in other pathologies of viral or bacterial nature. This leaves open a wide field of study in the use of the extract.
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