Giant cell arteritis

Authors

DOI:

https://doi.org/10.35954/SM2019.38.1.8

Keywords:

Arteritis, Giant Cell Arteritis, Polymyalgia Rheumatica, Vasculitis

Abstract

Giant cell arteritis is a chronic vasculitis that affects medium and large vessels, with a predilection for the temporal artery. Environmental factors that would act on susceptible individuals are invoked. It is the most frequent vasculitis in the elderly. It has a wide clinical spectrum of manifestations, so there should be a high degree of suspicion, since, depending on an early diagnosis, treatment can be rapidly decided and, in this way, minimize the risk of complications. Treatment should be started when facing clinical suspicion, without waiting for confirmatory paraclinical methods. Glucocorticoids remain the first-line treatment, given their rapid symptoms relief and normalization of inflammatory parameters, achieving the reduction of mortality. The use of other immunosuppressants has not shown favorable categorical results. Biological agents are indicated in selected cases due to
the therapeutic failure of glucocorticoids, although they are still under study. We present the case of a patient with this diagnosis, who presented as a complication, a cerebrovascular accident in the area of the vertebrobasilar artery, the oral glucocorticoid treatment was started early, and the patient presented a good response and favorable evolution, without later complications.

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Author Biographies

Liliana Daveri

Batallón “Cap. Manuel Artigas” de Infantería Mecanizado Nº 6. San José. Uruguay.

María Cardozo

Batallón “Rincón” de Infantería Mecanizado N° 9. Río Negro. Uruguay.

References

(1) Terrades-Garcia N1 Cid MC. Pathogenesis of giant-cell arteritis: how targeted therapies are influencing our understanding of the mechanisms involved. Rheumatology (Oxford) 2018; 57(suppl. 2):ii51-ii62. doi: 10.1093/rheumatology/kex423

(2) Schett G. Physiological effects of modulating the interleukin-6 axis. Rheumatology 2018; 57(suppl. 2): ii43-ii50. https://doi.org/10.1093/rheumatology/kex513

(3) Koster MJ, Matteson EL, Warrington KJ. Largevessel giant cell arteritis: diagnosis, monitoring and management. Rheumatology (Oxford) 2018; 57(suppl. 2):ii32-ii42. doi: 10.1093/rheumatology/kex424

(4) Banz Y, Stone JH. Why do temporal arteries go wrong? Principles and pearls from a clinician and a pathologist. Rheumatology (Oxford) 2018; 57(suppl_2):ii3-ii10. doi: 10.1093/rheumatology/kex524

(5) Grünholz D, Poblete M, Ovalle L, Wainstein E, Rubio G, Manríquez M, et al. Arteritis de células gigantes: compromiso extenso de la aorta y grandes ramas demostrado por tomografía por emisión de positrones. Caso clínico. Rev Méd Chile 2016; 144(11):1486-1490. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001100016&lng=es http://dx.doi.org/10.4067/S0034-98872016001100016

(6) Stone J. Foreword: clinical challenges of diagnosing and managing giant cell arteritis. Rheumatology (Oxford) 2018; 57(suppl. 2):1-ii2. https://doi.org/10.1093/rheumatology/key003

Published

2019-06-03

How to Cite

1.
Daveri L, Cardozo M. Giant cell arteritis. Salud Mil [Internet]. 2019 Jun. 3 [cited 2026 Apr. 19];38(1):67-73. Available from: https://revistasaludmilitar.uy/ojs/index.php/Rsm/article/view/24

Issue

Section

Case Reports

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