Posterior Reversible Posterior Leukoencephalopathy post eclampsia

Authors

  • Anabela Fernández Intensivist and Cardiologist. Coordinator of the High Risk Obstetrics Teaching Unit (UDA) and Coordinator of the Cardiology Unit of the C.T.I. of the Central Hospital of the Armed Forces (H.C.FF.AA.). https://orcid.org/0000-0001-8362-1846
  • Jorge Castelli Intensivist. Coordinator of the Multipurpose Sector of the Special Care Center of the H.C.FF.AA. https://orcid.org/0000-0002-9086-4915
  • Julio Citera Gynecotologist. Chief of the Department of Gynecology and Obstetrics of the H.C.FF.AA.
  • Risel Suárez Gynecologist, member of the High Risk Obstetrics Unit of the H.C.FF.AA.
  • Anela De Armas Intensivist. Intermediate Care Coordinator of the H.C.FF.AA., member of the High Risk Obstetrics Unit.
  • Gladys Germano Gynecologist, member of the High Risk Obstetrics Unit of the H.C.FF.AA.
  • Martín Mojoli Gynecologist, member of the High Risk Obstetrics Unit of the H.C.FF.AA. https://orcid.org/0000-0002-2418-3775

DOI:

https://doi.org/10.35954/SM2015.34.1.6

Keywords:

Pre-Eclampsia; Eclampsia; Birthing Centers; Postpartum Period; Hypertension; Brain Diseases

Abstract

We describe the clinical case of a 14-year-old female patient who presented post eclampsia with reversible posterior leukoencephalopathy syndrome (RPLS) in the early puerperium. This syndrome could be clinically evidenced and its tomographic objectification. RPLS presents in multiple clinical entities, including eclampsia. The patient presented at 38 weeks of gestation with eclampsia, the pregnancy was terminated by emergency cesarean section, and on the third day she had a repeated episode of seizure that ceased with the administration of magnesium sulfate. Subsequently, she developed bilateral amaurosis and paresis of the right upper limb. Two cranial tomography scans showed vasogenic edema of the white matter in the posterior cerebral area, which reverted after 72 hours both clinically and tomographically. Treatment was early, seizures were controlled and arterial hypertension was treated. The syndrome was reversed and the patient had no sequelae. In a patient with eclampsia that adds other neurological disorders, it is necessary to keep the RPLS in mind and quickly control the hypertension to prevent it from progressing to cerebral infarction.

Received for review: December 2014

Accepted for publication: March 2015

Correspondence: 8 de Octubre 3020 C.P. 11600, Montevideo, Uruguay. Tel: (+598)24876666 ext. 3330.

Contact e-mail: anabelafm@telefonica.net

 

 

 

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References

(1) Hinchey J, Chaves C, Appignani Bet, et. al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med 1996; 334(8):494-500.

(2) Garg R. Posterior leukoencephalopathy syndrome. Postgrad Med J 2001; 77(903):24-8.

(3) Schwartz R, Jones K, Kalina P, Bajakian R, Mantello M, Garada B, et al. Hypertensive encephalopathy: findings on CT, MR imaging and SPECT imaging in 14 cases. Am J Roentgenol 1992; 159(2):379-8.

(4) Jarosz J, Howlett D, Cox T, Bincham J. Cyclosporine related reversible posterior leukoencephalopathy: MRI. Neuroradiology 1997; 39(10):711-5.

(5) Kamar N, Kany M, Bories P, Ribes D, Izopet J, Durand D, Rostaing L. Reversible posterior leukoencephalopathy syndrome in hepatitis virus C positive long-term hemodialysis patients. Am J Kidney Dis 2001; 37(4): E29.

(6) Castelli J, Medina J, Greco G, Roca A.Leucoencefalopatía secundaria a neurotoxicidad por anticalcineurínicos. V Jornadas Internacionales de Neurointensivismo, 2013 junio 12-15; Buenos Aires. Argentina.

(7) ACOG Committee on Obstetric Practice. Practice bulletin no. 33: diagnosis and management of preeclampsia and eclampsia. Obstetrics & Gynecology 2002; 99(1):159-167.

(8) Hirshfeld-Cytron J, Lam C, Karumanchi SA, Lindheimer M. Late postpartum eclampsia: examples and review. Obstet Gynecol Surv 2006; 61(7):471-80.

(9) Servillo G, Bifulco F, De Robertis E, Piazza O, Striano P, Tortora F, et al. Posterior reversible encephalopathy syndrome in intensive care medicine. Intensive Care Med 2007; 33: 230-6.

(10) Stott V, Hurrell M, Anderson T. Reversible posterior leukoencephalopathy síndrome: a misnomer reviewed. Intern Med J 2005; 35(2):83-90.

(11) Prasad N, Gulati S, Gupta RK, Kumar R, Sharma K, Sharma RK. Is reversible posterior leukoencephalopathy in patients with severe hypertension completely reversible in all patients? Pediatr Nephrol 2003; 18(11):1161-8.

(12) Report of de National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000; 183(1):S1-S22.

(13) Domínguez R. Famulari A, Vila J. Leucoencefalopatía: la frontera entre lo reversible y lo persistente. Rev Neurol 1997; 25(148):2074.

(14) Cunningham F, Twickler D. Cerebral edema complication eclampsia. Am J Obstet Gynecol 2000; 182(1Pt 1):94-100.

Published

2015-06-30

How to Cite

1.
Fernández A, Castelli J, Citera J, Suárez R, De Armas A, Germano G, et al. Posterior Reversible Posterior Leukoencephalopathy post eclampsia. Salud Mil [Internet]. 2015 Jun. 30 [cited 2025 Nov. 5];34(1):41-5. Available from: https://revistasaludmilitar.uy/ojs/index.php/Rsm/article/view/198

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Case Reports

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