Twin pregnancy in a patient with dilated cardiomyopathy

Authors

DOI:

https://doi.org/10.35954/SM2025.44.2.7.e503

Keywords:

cardiomyopathy, dilated, pregnancy complications, cardiovascular, pregnancy, twin, myocardium /diagnostic imaging, stroke volume

Abstract

Introduction: There are few reports of women with dilated cardiomyopathy who have decided to become pregnant, as people with this condition are advised not to conceive.  If this does happen, it must be carefully assessed by a multidisciplinary team due to the risk of cardiac failure, arrhythmias, and/or other complications that increase maternal and fetal morbidity and mortality.

Clinical case: We report the case of a 31-year-old patient with dilated cardiomyopathy, with a left ventricular ejection fraction of 38% on echocardiogram, who had a high-risk twin pregnancy.

Results: The pregnancy was terminated at 34 weeks, resulting in two newborns without pathologies and with good maternal evolution.

Discussion: Pregnant women with dilated cardiomyopathy and reduced left ventricular ejection fraction are at increased risk of complications such as heart failure, acute pulmonary edema, potentially dangerous arrhythmias, sudden death, premature delivery, and fetal death. In twin pregnancies, the risk is increased due to the greater increase in blood volume and the additional demand on the heart.

Conclusions: The assessment and monitoring of a pregnant patient with dilated cardiomyopathy should be carried out by a multidisciplinary team specializing in obstetrics and cardiology.

Note: This article was approved by the Editorial Committee.

Received for review: February 2025.
Accepted for publication:
June 2025.
Correspondence:
8 de Octubre 3020, C.P. 11100. Tel.: (+598) 24876666 ext. 3330. Montevideo, Uruguay.
Contact email: 
anabelafm@telefonica.net

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Author Biographies

Anabela Fernández, Hospital Central de las Fuerzas Armadas

CONTRIBUTED TO THE MANUSCRIPT IN: Conception, design, data acquisition and analysis, interpretation and discussion of results, writing, critical review, and final approval.

Jorge Castelli, Hospital Central de las Fuerzas Armadas

National Directorate of Health of the Armed Forces. Central Hospital of the Armed Forces. Teaching and Healthcare Unit for the prevention, diagnosis, and treatment of serious and potentially serious pathologies in obstetrics. Montevideo, Uruguay.

CONTRIBUTED TO THE MANUSCRIPT BY: Writing and critical review.

Ignacio Farro, Hospital Central de las Fuerzas Armadas

National Directorate of Health of the Armed Forces. Central Hospital of the Armed Forces. Teaching and Healthcare Unit for the prevention, diagnosis, and treatment of serious and potentially serious pathologies in obstetrics. Montevideo, Uruguay.

CONTRIBUTED TO THE MANUSCRIPT BY: Data acquisition and analysis, writing, and critical review.

References

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Owens A, Yang J, Nie L, Lima F, Avila C, Stergiopoulos K. Neonatal and Maternal Outcomes in Pregnant Women With Cardiac Disease. J Am Heart Assoc 2018 Nov 6; 7(21):e009395. https://doi.org/10.1161/JAHA.118.009395 PMID: 30571384.

Roos-Hesselink JW, Ruys TP, Stein JI, Thilén U, Webb GD, Niwa K, et al. Outcome of pregnancy in patients with structural or ischaemic heart disease: results of a registry of the European Society of Cardiology. Eur Heart J 2013 Mar; 34(9):657-65. https://doi.org/10.1093/eurheartj/ehs270 PMID: 22968232.

European Society of Gynecology (ESG), Association for European Paediatric Cardiology (AEPC), German Society for Gender Medicine (DGesGM), Regitz-Zagrosek V, Blomstrom Lundqvist C, Borghi C, et al. ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC). Eur Heart J 2011 Dec; 32(24):3147-97. https://doi.org/10.1093/eurheartj/ehr218 PMID: 21873418.

Regitz-Zagrosek V, Roos-Hesselink JW, Bauersachs J, Blomström-Lundqvist C, Scientific Document Group, et al. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy. Eur Heart J 2018 Sep 7; 39(34):3165-3241. https://doi.org/10.1093/eurheartj/ehy340 PMID: 30165544.

Moghbeli N, Pare E, Webb G. Practical assessment of maternal cardiovascular risk. Congenit Heart Dis 2008; 3(5):308-16. https://doi.org/10.1111/j.1747-0803.2008.00207.x PMID: 18837808.

Published

2025-09-05

How to Cite

1.
Fernández A, Castelli J, Farro I. Twin pregnancy in a patient with dilated cardiomyopathy. Salud Mil [Internet]. 2025 Sep. 5 [cited 2025 Nov. 5];44(2):e503. Available from: https://revistasaludmilitar.uy/ojs/index.php/Rsm/article/view/457

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Case Reports

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